Restoring perfusion without cutting bone.
Periosteal distraction gently elevates the periosteum from the tibial cortex, then lets it retract — recruiting new blood supply through the bone to heal ischemic and diabetic lower-limb wounds. No osteotomy. No bone transport.
When a wound won't heal, the problem is usually blood supply.
Chronic limb-threatening ischemia and diabetic foot ulcers stall because the tissue is starved of perfusion. Five-year mortality after major amputation rivals many cancers. When revascularization is exhausted, periosteal distraction offers a way to coax the body into building its own new circulation — without removing or transporting a segment of bone.
Limited inflow
Peripheral arterial disease and microvascular damage leave wound beds without the perfusion needed to close.
Exhausted options
Even after successful revascularization, distal micro-ischemia can perpetuate non-healing ulcers.
The cost of cutting
Bone-transport techniques require a corticotomy — a deliberate surgical cut with its own morbidity and consolidation time.
One principle: controlled tension creates new blood vessels.
Both periosteal distraction and transverse tibial transport rest on Ilizarov's tension-stress principle — gradual, controlled distraction of living tissue triggers regeneration and angiogenesis. The difference is only what is distracted.
Tension
A device applies slow, sub-millimeter daily distraction to the periosteum (PD) or a cortical window (TTT).
Signaling
Mechanical strain upregulates VEGF, bFGF, PDGF and related growth factors, recorded across multiple cohorts.
Angiogenesis
New collateral vessels and a richer vascular network form in the limb, visible on CT angiography and perfusion imaging.
Healing
Improved distal perfusion supports wound closure and limb salvage, with reduced amputation and recurrence.
Four phases of a single, cortex-sparing idea.
A low-profile subperiosteal plate is fixed to the medial tibia through a small incision. Over days it gently elevates the periosteum from the bone, then lets it settle back — triggering the angiogenic and osteogenic response that perfuses the limb.
A · Placement
Through a roughly 1 cm incision, a low-profile plate is placed under the periosteum on the medial tibia and linked to the fixator. The periosteum sits flush against the intact cortex — no bone is cut.
A measured course, not a single operation.
Periosteal distraction follows the principles of distraction osteogenesis. Reported parameters in the literature include distraction rates around 0.5–0.75 mm/day and total elevation up to ~10 mm.
Placement
The subperiosteal plate is implanted and linked to the fixator; soft tissues are allowed to settle.
Distraction
The periosteum is gradually elevated over roughly two weeks, opening the osteogenic and angiogenic space.
Consolidation
The periosteum settles back as newly recruited vasculature and bone mature in place.
Removal
The low-profile device is removed; with no osteotomy, there is no bone cut to consolidate.
Two expressions of the same biology.
Transverse tibial transport (TTT) established that mechanical distraction can drive angiogenesis and has the deeper evidence base. Periosteal distraction (PD) pursues the same biological goal while leaving the cortex intact. They are complementary tools.
Both techniques share the same destination — inducing new perfusion to save a limb. We regard them as partners in the same mission, and present the full evidence for each.
The peer-reviewed literature, organized and current.
Primary sources for periosteal distraction and the broader transverse-tibial-transport body of work — with verified DOIs.
Periosteal Distraction
Transverse Tibial Transport
Independent resources on limb salvage.
Plain-language, evidence-based references for clinicians and patients facing amputation — covering both distraction techniques and the shared goal of saving limbs.
The mechanism, protocol and evidence for periosteal distraction.
The transverse tibial transport literature and technique, in depth.
Visit →Limb-salvage options when amputation has been raised — for patients and families.
Visit →Questions about the procedure or the evidence?
This is an independent clinical resource. Reach out to discuss the published literature, the mechanism, or how periosteal distraction fits into a limb-salvage pathway.